In the study, titanium-coated PEEK, smooth PEEK and NuVasive Porous PEEK interbody implants were subjected to impaction loading conditions. Analysis of Porous PEEK showed the surface structure maintained a high porosity (>65 percent) and exhibited minimal changes to pore size and depth following impaction. This maintenance of porosity and pore depth gives a surgeon confidence that the porous architecture will not collapse during insertion. The titanium-coated devices demonstrated titanium coating loss after impaction that was corroborated with a decrease in surface roughness. Smooth PEEK showed minimal signs of damage, but demonstrated a decrease in surface roughness.
"The findings in this study are significant because they demonstrate the durability and impaction resistance of interbody implants made from Porous PEEK," said Kevin T. Foley, M.D. "Knowing the porous structure is seamlessly integrated with the implant, without sacrificing implant strength, and that the implant maintains porosity following impaction means that the opportunity for bony ingrowth is optimized."
Porous PEEK is manufactured through a proprietary extrusion process which produces a unified porous-to-solid structure designed to enhance osseointegration and maximize bone-to-implant contact. Available for cervical and thoracolumbar applications, Cohere and Coalesce Interbody Fusion Devices are the only Porous PEEK interbody implants available in the market.
"Porous PEEK exemplifies our focus on disruptive technology and materials science. Born out of years of pre-clinical research, this durable implant technology combines the inherent benefits of porosity with the advantageous material properties of PEEK," said Matt Link, executive vice president, strategy, technology and corporate development for NuVasive. "Designed for enhanced osseointegration, biomechanical, and imaging properties, Porous PEEK and the entire NuVasive Advanced Materials Science portfolio, which also includes Modulus titanium interbody implants, represent the future of porous implant technologies."
NuVasive Inc.'s portfolio includes access instruments, implantable hardware, biologics, software systems for surgical planning, navigation and imaging solutions, magnetically adjustable implant systems for spine and orthopedics, and intraoperative monitoring service offerings. With over $1 billion in revenues, NuVasive has an approximate 2,400 person workforce in more than 40 countries serving surgeons, hospitals and patients.
1. Torstrick, B., Klosterhoff, B., Westerlund, E., Foley, K., Gochuico, J., Lee, C., Gall, K., Safranski, D. (2018). Impaction durability of porous polyether-ether-ketone (PEEK) and titanium-coated PEEK interbody fusion devices. The Spine Journal. Doi: 10.1016/j.spinee.2018.01.003