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    The FDA’s Flip-Flop on Hyaluronic Acid

    Offering an introduction to this treatment modality for osteoarthritis, this article also looks at recent changes at FDA.

    The FDA’s Flip-Flop on Hyaluronic Acid
    Mike Daley, CEO, OrthogenRx02.10.21
    Osteoarthritis (OA) is a degenerative disease of the synovial joints, which causes joint pain and functional impairment. It occurs frequently in adults over 50 years old and is a major cause of disability worldwide. OA is a progressive disorder, primarily affecting the cartilage found on the ends of bones in joints, with different degrees of disease severity that requires long-term management.
     
    Over the course of the disease, various options are available to treat the symptoms including non-pharmacologic, pharmacologic, and surgical treatment regimes. In the absence of a cure for OA, there are multiple systemic, oral medications available over-the-counter and by prescription that are commonly used to manage the pain associated with OA. These can include acetaminophen (Tylenol), opioids (Tramadol, Oxycontin, etc.), and non-steroidal anti-inflammatory drugs (NSAIDs; Advil, Aleve, Celebrex, etc.). When administered over a long time for a ch

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