Advita Ortho Begins Clinical Use of Activit-E Reverse Shoulder Liners

Advita Ortho announced the first clinical use of reverse shoulder humeral liners manufactured with its Activit-E vitamin E polyethylene for the Equinoxe reverse shoulder system.

The first procedures were performed by Thomas Wright, M.D., at the University of Florida.

“Whenever I plan my cases, I look for products and technologies that provide the ability to enhance my patients’ outcome,” said Dr. Wright. “The improved polyethylene wear properties of Activit-E combined with the impressive clinical success of the Equinoxe Reverse Shoulder System have the potential to improve my patients’ lives.”

The new reverse humeral liners are available for the company’s platform stem, small reverse baseplates, and fracture stem. With the launch, Activit-E polyethylene is now available across Advita’s shoulder, knee, and ankle implant portfolios.

Activit-E incorporates vitamin E into ultra-high-molecular-weight polyethylene (UHMWPE) before processing. The material is compression molded, annealed, gamma irradiated, and then machined into the final implant components. According to the company, the manufacturing process is designed to improve long-term oxidative stability while maintaining the material’s mechanical properties.

The humeral liners are being introduced through a limited U.S. pilot launch, with broader U.S. availability planned for the fourth quarter of 2026. Limited international availability is also planned.

“This milestone reflects Advita’s continued commitment to expanding meaningful innovations across our portfolio,” said Aurelio Sahagun, Advita Ortho’s CEO. “With the Activit-E polyethylene now available across our shoulder, ankle and knee systems, we’re providing surgeons with another advanced material option designed to enhance surgical outcomes.”

Earlier this month, the company revealed a series of new peer-reviewed studies supporting the continued evolution of its Newton knee-balancing intelligence, advancing the potential for more predictive, measurement-based decision-making in total knee arthroplasty.