Zimmer Spine Rolls Out New DBM Line

Zimmer Spine Inc. has launched its Puros line of demineralized bone matrix (DBM) with reverse phase medium (RPM) putty, putty with chips, gel and paste, and Puros DBM block and strip products. They are bone graft substitutes used to stimulate natural bone formation processes in surgical spine procedures.

Products are provided in collaboration with AlloSource, a Centennial, Colo.-based non-profit organization that offers more than 200 types of bone, skin, soft-tissue and custom machined allografts.

“We have had tremendous interest in these products leading up to the launch,” said Steve Healy, president of Minneapolis, Minn.-based Zimmer Spine. “Adding these six new lines to our portfolio will provide surgeons with a competitive, off-the-shelf, and convenient allograft at a good value to the hospital.”

Puros DBM with RPM products composed of demineralized bone matrix in a reverse phase medium. They are designed to stimulate natural bone formation processes, in which mesenchymal cells differentiate into bone-forming cells. According to the company, Puros DBM with RPM products contain a unique reverse phase medium, allowing the allograft to be malleable at operating room temperatures, while causing the product to stiffen when placed in the operating site. This property helps contains the DBM at the surgical site with minimal loss through irrigation and suction.

Puros DBM block and strip are unique bone graft substitutes composed of 100 percent demineralized cancellous bone. The allografts provide scaffolds for new bone growth and are processed to retain osteoinductive properties by preserving endogenous growth factors including BMP2, BMP4 and BMP7 to help support new bone formation. They are used during surgical procedures to help promote bone growth and joint stability. Puros DBM block and strip are flexible and compressible once rehydrated, and are available in a variety of sizes and shapes to reduce transplant preparation time, company officials noted.

The products officially will be unveiled during the American Association for Neurological Surgeons meeting held April 5-9 in San Francisco, Calif.

Headquartered in Warsaw, Ind., Zimmer makes orthopedic reconstructive, spinal and trauma devices, dental implants, and related surgical products.