• Login
    • Join
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Exclusives
    • Manufacturing
    • Markets
    • Top 10
    • Buyers' Guide
    • Events
    • Microsites
    • More
  • Magazine
  • News
  • Exclusives
  • Manufacturing
  • Markets
  • Top 10
  • Buyers' Guide
  • Events
  • Microsites
  • Current & Past Issues
    Features
    Departments
    Columns
    Editorial
    Digital Edition
    Subscribe Now
    Advertise Now
    Editorial Guidelines
    eNewsletter Archive
    eBook
    Top Features
    Orthopedic Implants Are Fit to Print

    Fitting the Mold of Ortho Device Manufacturing

    Artificially Intelligent Design for Orthopedic Devices

    Shoulder Technology Isn't Made 'Off the Cuff'

    Instrument Manufacturing Leads Toward Smarter Surgeries
    Breaking News
    Certifications
    Clinical Trials
    Device Approvals & Patents
    Financial & Deals
    International
    Market Data & Trends
    OEM News
    Orthopedic Innovators
    People
    Product & Service Releases
    Products
    Quality, Recalls & Risk
    Regulatory & Legal
    Supplier & Contract Mfg.
    Live From Shows
    Top News & Features
    Collagen Matrix Rebrands to Regenity Biosciences

    OsteoBoost Study Yields Positive Results

    Conventus Flower Ortho Appoints Jeff Culhane as COO

    Solid Growth Forecast for OTC Braces and Supports Market

    Exactech Boosts AI Expertise with Licensing Deal, Team of Scientists
    3-D Printing/Additive Mfg.
    Assembly & Automation
    Biocompatibility & Testing
    Clean Room
    Coatings/Surface Modification
    Contract Manufacturing
    Design
    Extrusion
    Finishing
    Forging & Casting
    Instruments, Cases & Trays
    International/Offshoring
    Laser Processing
    Materials
    Machining & Tooling
    Molding
    Packaging & Sterilization
    Prototyping
    Research & Developement
    Software & Quality
    Staffing, Training & Prof. Dev.
    Supply Chain

    ODT's Most-Read Stories This Week—March 25

    Switching Sterilization: What Should You Consider When Changing Processes?

    The MDR Delay’s Impact on Regulatory and Testing—An Orthopedic Innovators Q&A

    Navigating the EU MDR UDI Requirements: The Benefits and Challenges

    How 3D Printing is Impacting the Orthopedic Industry
    Biologics
    Bracing/Prosthetics
    Extremities
    Imaging
    Instruments
    Large Joint
    MIS/Robotics
    Spine/Neurology
    Trauma/Sports
    Top Markets
    Enabling Technologies: The Future of Differentiation in Spinal Surgery

    Potential Applications of Continuous Carbon Fiber-Reinforced Additive Manufacturing

    X-Ray Sterilization Considered a 'Game-Changer' for Orthopedic Industry

    Medtech Firms Turning to Rigid Containers Amid Sterilization Wrap Shortage

    7 Ways Design Can Impact Orthopedic Manufacturing Costs
    Companies
    Categories
    Company Capabilities
    White Papers
    Add New Company
    International Buyers Guide Companies
    Modern Plastics

    Braxton Manufacturing

    Life Science Outsourcing Inc.

    AV&R

    Tiodize
    Industry Events
    Webinars
    • Magazine
      • Current & Past Issues
      • Features
      • Editorial
      • Departments
      • Columns
      • Digital Edition
      • eNewsletter Archive
      • Editorial Guidelines
      • Subscribe Now
      • Advertise Now
      • eBook
    • Breaking News
    • Buyers' Guide
      • Companies
      • Categories
      • Company Capabilities
      • White Papers
      • Add Your Company
    • Manufacturing
      • 3-D Printing/Additive Mfg.
      • Assembly & Automation
      • Biocompatibility & Testing
      • Clean Room
      • Coatings/Surface Modification
      • Contract Manufacturing
      • Design
      • Extrusion
      • Finishing
      • Forging & Casting
      • Instruments, Cases & Trays
      • International/Offshoring
      • Laser Processing
      • Materials
      • Machining & Tooling
      • Molding
      • Packaging & Sterilization
      • Prototyping
      • Research & Developement
      • Software & Quality
      • Staffing, Training & Prof. Dev.
      • Supply Chain
    • Markets
      • Biologics
      • Bracing/Prosthetics
      • Extremities
      • Imaging
      • Instruments
      • Large Joint
      • MIS/Robotics
      • Spine/Neurology
      • Trauma/Sports
    • Top 10
    • Online Exclusives
    • Slideshows
    • Videos
    • Webinars
    • Events
      • Industry Events
    • Live from Show Event
    • About Us
      • About Us
      • Contact Us
      • Privacy Policy
      • Terms of Use
      • Advertise With Us
    Online Exclusives

    Biologics' Backbone

    The explosion in spinal fusion procedures is leading to the development of innovative regenerative treatments.

    Biologics
    A 3-D rendering of blood vessels (red) and osteoblasts (blue) are shown growing into the interconnected porosity of Biogennix's bone graft substitute. Image courtesy of Biogennix.
    Michael Barbella, Managing Editor03.18.19
    Christopher J. Centeno, M.D., could arguably be considered the “father” of regenerative medicine. He claims, after all, to be the first person on the planet to perform stem cell injections to treat joint arthritis and various other conditions.
     
    There are several worthy contenders, including Arnie Caplan, Ph.D., pioneer of mesenchymal stem cell use (late 1980s); Philippe Henigou, developer of bone marrow concentrate treatment for bone disease (early 1990s); or Svante Gehring, M.D., the first physician to document use of platelet-rich plasma in ophthalmology (1999).
     
    Centeno, however, believes the title should go to Ohio surgeon George S. Hackett, M.D., who clinically and scientifically demonstrated the efficacy of irritating tissue to promote healing back in 1963. Hackett’s studies showed that creating controlled inflammation could increase ligament size by up to 35-40 percent (more recent analyses have confirmed those initial findings).
     
    While certainly revolutionary, Hackett’s work nevertheless was pre-dated by several thousand years: The concept of irritating tissue to promote healing actually ori

    Continue reading this story and get 24/7 access to Orthopedic Design Technology for FREE


    FREE SUBSCRIPTION
    Already a subscriber? Login
    Related Searches
    • spinal fusion
    • resorbable
    • regeneration
    • synthetic
    Suggested For You
    Steri-Tek Steri-Tek
    Extremely Simple and Efficient Extremely Simple and Efficient
    Extremely High Expectations Extremely High Expectations
    Researchers Uncover Aspirin’s Effects on Platelet-Rich Plasma Researchers Uncover Aspirin’s Effects on Platelet-Rich Plasma
    Empowering the Six Percent Empowering the Six Percent
    Bioventus Launches OSTEOAMP SELECT Fibers Bioventus Launches OSTEOAMP SELECT Fibers
    Disrupting the Ceramic Bone Graft Substitute Sector Disrupting the Ceramic Bone Graft Substitute Sector
    Unconventional Solutions Unconventional Solutions
    Orthobiologics Orthobiologics' Precious Balance
    Orthobiologics Orthobiologics' High Reward
    Natural Selection: Biologics in Orthopedics Natural Selection: Biologics in Orthopedics
    Biogennix Names Chief Financial Officer Biogennix Names Chief Financial Officer
    Sounding Board: 2018 Reflections and Looking Ahead Sounding Board: 2018 Reflections and Looking Ahead

    Related Buyers Guide Companies

    • Steri-Tek

      Steri-Tek

      ...
      Jeff Sauter, Director Business Development 05.26.22

    • Extremities
      Extremely Simple and Efficient

      Extremely Simple and Efficient

      With more patients becoming engaged in their health, small joint device makers are designing easier, more effective treatments.
      Michael Barbella, Managing Editor 06.10.19

    • Extremities
      Extremely High Expectations

      Extremely High Expectations

      Patients are demanding small-joint solutions that eliminate pain and restore a high level of function.
      Michael Barbella, Managing Editor 06.04.19


    • Researchers Uncover Aspirin’s Effects on Platelet-Rich Plasma

      Researchers Uncover Aspirin’s Effects on Platelet-Rich Plasma

      Blood thinners have a negative effect on PRP, data show.
      Baylor College of Medicine 05.08.19

    • Empowering the Six Percent

      Empowering the Six Percent

      First female AAOS president working to remove barriers to inclusion within orthopedics.
      Michael Barbella, Managing Editor 04.26.19

    Loading, Please Wait..

    Trending
    • Missouri Neurosurgeon Settles Federal Kickback Lawsuit For $825K
    • Enabling Technologies: The Future Of Differentiation In Spinal Surgery
    • Össur Unveils Rebound ACL Brace
    • Spinal Stabilization Technologies Begins LOPAIN2 Trial In South America
    • AAOS News: Mark S. Myerson Receives 2023 Humanitarian Award
    Breaking News
    • Collagen Matrix Rebrands to Regenity Biosciences
    • OsteoBoost Study Yields Positive Results
    • Conventus Flower Ortho Appoints Jeff Culhane as COO
    • Solid Growth Forecast for OTC Braces and Supports Market
    • Exactech Boosts AI Expertise with Licensing Deal, Team of Scientists
    View Breaking News >
    CURRENT ISSUE

    March/April 2023

    • Fitting the Mold of Ortho Device Manufacturing
    • Artificially Intelligent Design for Medical Devices
    • Orthopedic Implants Are Fit to Print
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    Kemin Human Nutrition & Health Acquires Oral Health Ingredient
    Wiley Eliminates Outer Carton From Packaging to Reduce Waste
    ACG Expands as Vantage Nutrition Acquires ComboCap and its Dual-Chamber Capsule Technology
    Coatings World

    Latest Breaking News From Coatings World

    PPG Names Rodolfo Ramirez GM, Packaging Coatings
    Sherwin-Williams Unveils High Performance Interior Marine Decking Systems
    AkzoNobel Appoints Ricardo Rosso as Pontiac Site Manager
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    Apply Now: Junkosha's Technology Innovator of the Year Awards 2023
    SIS Medical's OPN NC PTCA Dilatation Catheter Released in U.S.
    Digital Transformation Weighs Heavy in Medtech Regulatory Performance
    Contract Pharma

    Latest Breaking News From Contract Pharma

    Thermo Fisher, Arsenal Biosciences Partner to Manufacture Autologous T-Cell Therapies
    Aquestive Therapeutics Expands Libervant License/Supply Agreement with Pharmanovia
    OncoVent, Orient EuroPharma Enter License Agreement for Oregovomab
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    Sexual Wellness Brand Playground Recruits Christina Aguilera
    Buttah Skin Founder Wins Emerging Brand Partner of the Year Award from Macy’s
    L’Oréal Wins Legal Battle Over “Paris” Product Labels
    Happi

    Latest Breaking News From Happi

    Kao Launches Space Shampoo Sheet for Haircare
    Indie Personal Care and Skincare Brand Indigo Wild Mainstreams Geranium-Patchouli Scent
    Procter & Gamble Brings Tide Relief Project to Mississippi Tornado Victims
    Ink World

    Latest Breaking News From Ink World

    INX International Makes Investment in Gooten
    Videojet Launches 1580 C Soft-Pigmented Contrast Printer
    Epson to Showcase Textile, Signage and Aqueous Printers at ISA 2023
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    Industrias Omega adds Durst Tau RSC E
    Ahlstrom publishes 2022 sustainability report
    INFOFLEX 2023 to feature 20+ press manufacturers
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    SharpCell Launches Plastic-free Airlaid Material for Premium Napkins
    Suominen Offers Biolace Ultrasoft
    Maxcess Offers More Engineering and Converting Solutions for Iberia
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    Collagen Matrix Rebrands to Regenity Biosciences
    OsteoBoost Study Yields Positive Results
    Conventus Flower Ortho Appoints Jeff Culhane as COO
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    Universal Display Sponsors, Presents at ICDT 2023
    Miron Washington Joins Impinj Board of Directors
    All-Time High for Global 300MM Semiconductor Capacity in 2026: SEMI

    Copyright © 2023 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login